They seal on all four sides.
They seem to heal better with the antibiotic, but, in my opinion, not as good as with the antibiotic applied separately.
They repackaged this assortment in a new box that only shows the larger 1in. x 3in. bandage anywhere on the box. On the front of the box in fine print, it says that it contains assorted sizes. On the side of the box in fine print it says that there are 10 of the large size and 10 of the small size. But they have removed the miniaturized graphics showing both sizes in their proportions. When in need, you could just grab the old box and quickly see that there are two sizes in the box, select one and go. I found myself looking around in the first aid kit for a smaller bandage when all along they were in this new box but not displayed.
The bottom line is that the new box is deceptive by giving the visual impression that the entire box is of the large size bandage. When you are in a rush, which is most of the time when you are in need of a bandage, you don't have time to stop and read their fine print. Since showing only the large bandage is the only obvious change to the box, it is clear that J&J made this redesign intentionally. Having taken the efficiency out of immediate care, two stars need to removed.
I don't recommend this newly boxed product.
No, I would not recommend this product